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Preface In the early 1990s, the first edition of this text helped to define the body of knowledge encompassed by neurotol- ogy, which was then a relatively new field. Over the past decade, major strides have been realized on a number of fronts. In terms of specialty organizations, the American Neurotology Society has grown to over 500 members. Across the Atlantic, neurotology has been organized through the European Academy of Otology and Neurotology, an active group of some 300 members. Perhaps no aspect of neurotology has undergone a greater degree of maturation than training. In the United States, two- year post-residency fellowships are now formally accredited by the American Council of Graduate Medical Education. As of early 2004, approximately 20 fellowship programs are active, 10 of which have completed the accreditation process. In a major milestone, neurotology has become the first subspecialty of Otolaryngology–Head and Neck Surgery to achieve board certification by the American Board of Otolaryngology. In the clinical realm, a sizable and ever increasing num- ber of practitioners are focusing their professional efforts in neurotology. In the operating room, microsurgical tech- nology continues to evolve with improved microscope and drill systems, image guidance, and more capable neuro- physiologic equipment to mention just a few advances. In tumor surgery, the emphasis continues to be on develop- ment of minimally invasive techniques that maximize tumor control while optimizing neural preservation. Innovative radiotherapy methods, particularly stereotactic techniques, have developed a role in selected neurotologic tumors. In the vestibular field, numerous new therapies have been devised for BPPV and entire new diagnoses, such as superior semicircular canal dehiscence, have been introduced. Research in the field is robust. The National Institute of Deafness and Other Communication Disorders budget has risen from $166.8 million in 1995 to $380.4 million in 2004—a large fraction of which is dedicated to investigation of the ear and auditory nervous system. Among the numer- ous fruits of this investment are over 60,000 cochlear implant devices placed worldwide and the continued refinement of the auditory brainstem implant. Programs have been initiated in the development of a vestibular pros- thesis. In genetics, over 100 genes for hereditary hearing impairment have been localized, a significant portion of which have been cloned. In neurotologic tumors, great strides have been made in understanding the molecular genetic basis for acoustic neuroma, NF-2, paragangliomas, and papillary adenocarcinomas of the endolymphatic sac. Functional imaging, in which the chemical processes within the brain and other tissues are mapped, also has a promising future. Looking forward a few decades, it seems probable that the first human sense to be directly coupled with implanted digital devices on a routine basis will be the ear. It can be envisioned that man-machine interaction with computers and communication devices will revolu- tionize how the ear is used. The companion surgical atlas to this text, promised in the preface of the first edition, was published in full color in 1996 (Jackler RK: Atlas of Neurotology and Skull Base Surgery. St. Louis, Mosby, 1996). A second edition is being contemplated at present. With the digital publishing revo- lution currently in full force, it can be envisioned that future editions of these works will appear primarily on the internet. Over the last few decades, neurotology has achieved critical mass as a field, both through the number of scientists and clinicians engaged in it as well as through the steady accumulation of new knowledge and clinical capabilities. The editors hope that this comprehensive resource, as the primary textbook in the field, will serve to foster excellence and stimulate innovation in neurotology. Robert K. Jackler, MD Derald E. Brackmann, MD vii