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INDEX A Acquired childhood epileptic aphasia, s e e Landau- Kleffner syndrome ADD, s e e Attention deficit disorder ADE s e e Aphasia Diagnostic Profiles Aging, s e e Senescence Agrammatism Cross-Language Agrammatism Study, 223-224 definition, 222-223, 249-250 history of study, 30, 49-53 lexical representation and access, 228 parametric variation of languages, 224-228 sentence production adaptive strategies, 259 constructional aspect, 256, 258 linguistic-descriptive approach to agrammatic production, 256-257 morphological aspect, 255-258 nonfluency, 256, 258-259 processing approach to agrammatic production, 258-259 verb naming deficits, 5 AI, s e e Artificial intelligence Alexia, s e e Pure alexia Alexithymia brain damage as cause, 308 bulimia nervosa association, 309 Algebra, s e e Number processing Alzheimer's disease, s e e Dementia of the Alzheimer's type American Sign Language (ASL) aphasia comprehension, 322-323 fluent aphasia and lesions, 325 morphology errors, 322 nonfluent aphasia and lesions, 324-325 phonemic paraphasias, 320-321 production of language, 320 right-hemisphere-damaged signers classifier production impairment, 326-327 discourse impairment, 326 syntactic comprehension, 327-328 syntax errors, 322 apraxia, 328-329 classifiers, 315 discourse, 316 event-related potential studies, 119-120 facial expressions, 315-316 fingerspelling, 316-317 hemispheric specialization in deaf, 202-203, 317-320, 323-329 individual variability in signing skills, 314 morphology, 315 phonology, 315 syntax, 316 Amobarbital test, s e e Intracarotid sodium amytal test Angular gyrus maturation, 19 role in aphasia recovery, 185 A n l a g e n , ontogenesis, 17-18 Anomia lesion site analysis, 132 noun naming deficits, 5 treatment studies, 570 APA, s e e Arcuate premotor area Aphasia, s e e a l s o s p e c i f i c a p h a s i a s aging effects on types, 364-365 central executive role in language processing, 296-297 computational transcript analysis, s e e Child Language Data Exchange System discourse impairments, 268-269 evaluation, s e e s p e c i f i c t e s t s history of research, 13-15, 30, 32, 40, 43, 45-47, 54 laterality, 389-390 lesion site analysis, 131-132, 169-170, 182-183 models in therapy, 586 morphology breakdown, 221-234 phonetic errors, s e e Phonetic deficit 773 774 Index Aphasia ( c o n t i n u e d ) phonological errors, s e e Phonological deficit prosody deficits, s e e Prosody recovery, s e e Recovery, aphasia sign language aphasia, s e e American Sign Language single-word processing, s e e Single-word processing speech perception deficits, s e e Speech perception syntax disorders, s e e Syntactic processing type classification, 75, 169-170, 536 Aphasia Diagnostic Profiles (ADP), aphasia type classification, 75 Apraxia deaf signers, 328-329 lesion analysis, 185 Arcuate premotor area (APA), control, 168 Arithmetic, s e e Number processing Articulatory rehearsal process, s e e Working memory Artificial intelligence (AI), computer therapy in aphasia, 594-595 Artificial neural network, s e e Neural network modeling ASL, s e e American Sign Language Asperger's syndrome cognitive theories, 533 diagnosis, 532-533 Attention automatic processes, 275 definitions, 281-282 detecting function, 278-279 disorders attention deficit disorders, s e e Attention deficit disorder attentional dyslexia, 284-285 dementia of the Alzheimer's type, 285 neglect dyslexia, 283-284 eye movement in attention impairments, 279- 28O factorial structure, 277-278 focus-execute function, 278 frontal lobe functions, 283 movement without eye movement, 280-281 neural-network models, 277 orienting function, 278 selective attention, 275 testing COVAT paradigm, 276, 280 dichotic listening task, 276-277 functional brain imaging, 277 Stroop task, 276 Attention deficit disorder (ADD) classification, 286 event-related potential studies, 286 features, 285 right hemisphere role, 286-287 Attentional dyslexia, features, 284-285 Auditive cortex, maturation, 22 Auditory perception, s e e Dichotic listening task Auditory processes, dyslexia, 578-579 Augustine, contributions to neurolinguistics, 603 Autism, s e e a l s o Asperger's syndrome clinical spectrum, 527-528 cognitive theories developmental effects of mentalizing deficits, 530-532 language relationship, 532 overview, 528-529 theory of mind hypothesis, 529-532 diagnosis, 525, 527 incidence, 526 B Backprop algorithm, s e e Neural network modeling Basal ganglia, language role historical perspective, 431--433 infarction and hemodynamics in aphasia, 433- 435 Parkinson's disease and syntax comprehension deficits, 435-436 prosody role, 308 Basins of attraction, modeling of deep dyslexia, 237-238 Bastian, Henry Charlton, contributions to neurolinguistics, 47-49 BAT, s e e Bilingual Aphasia Test Bilingual Aphasia Test (BAT), development, 74 Bilingualism, s e e Multilingualism Binomial test model, 64 Blood-oxygenation level-dependent effect (BOLD), s e e Functional magnetic resonance imaging BNT, s e e Boston Naming Test BOAE, s e e Boston Diagnostic Aphasia Examination BOLD, s e e Blood-oxygenation level-dependent effect Boltzmann Machine algorithm, s e e Neural network modeling Bonnet, Charles, contributions to neurolinguistics, 32-33 Book listing, neurolinguistics, 644-652 Boston Diagnostic Aphasia Examination (BOAE) aphasia type classification, 75 Index 775 features and applications, 78-79, 81 software for scoring, 640 Boston Naming Test (BNT) cultural bias, 74 differential diagnosis, 74-75 features and applications, 80-81 Bouillaud, Jean Baptiste, contributions to neurolinguistics, 38-41 Brain-behavior relationships evolution, 160-161 limbic circuits, 166 neuromodulation, 164, 171 Brain-imaging, s e e Functional magnetic resonance imaging; Magnetoencephalography; Positron emission tomography Brain lesion, s e e Lesion analysis Brain-mapping, s e e Focal electrical stimulation; Functional magnetic resonance imaging; Lesion analysis; Magnetoencephalography; Neurolinguistic deficit space; Positron emission tomography Brain-stem, vertical organization of brain, 161 BrainTrainMedia, 620 Broca, Piere Paul, contributions to neurolinguistics, 41-43 Broca's aphasia, age of onset, 23 C CADL, s e e Communicative Abilities in Daily Living California Verbal Learning Test (CVLT), Parkinson's disease testing, 478-479 Case-deficit hypothesis, 252 Central executive, s e e Working memory Centralist hypotheses, dyslexia, 580-583 Centromedian nucleus (CM), language role, 438- 440 Cerebellum, evolution of language function, 169 Cerebral cortex, vertical organization of brain, 161 Cerebrum innate properties versus inventions of humankind, 19-21 ontogenesis, 17-19 Chance dissociations, 62 Child Language Analysis (CLAN), s e e Child Language Data Exchange System Child Language Data Exchange System (CHILDES) applications, 601 CHAT headers, 607 overview, 601 transcript format, 607-609 CLAN discourse analysis, 613 lexical analyses, 609, 611-612 morphosyntactic analyses, 612-613 overview of programs, 601, 610 phonological analysis, 613-615 crosslinguistic focus, 602 data entry, 615-616 database access formats, 606 contents, 606-607 overview, 601 funding, 600 history of development, 603-606 membership and access, 606-607, 615 modes of research, 601-602 CHILDES, s e e Child Language Data Exchange System CJD, s e e Creutzfeldt-Jakob disease CLAN, s e e Child Language Analysis CLAS, s e e Cross-Language Agrammatism Study Closed-class words, s e e Word-class CM, s e e Centromedian nucleus Coarticulation, deficits in aphasia, 211-212 CogniSpeed, 620-821 Cognitive neurolinguistics approach communication abnormalitiesin psychosis, 503- 504 language therapy, planning and evaluation, 70 Cognitive Rehabilitation Software, 621 COMLES-Familie Lernprogramme, 621-622 Commissurotomy, s e e Right hemisphere disconnection syndrome Communication, s e e a l s o Discourse differentiating from language, 526, 533 evolution, 160, 162-163, 168-169 neuroanatomy, 161-162 Communicative Abilities in Daily Living (CADL) aphasia severity assessment, 75, 77 features and applications, 78 Computed tomography (CT) lesion analysis, 175-178 perisylvian regions, anatomical asymmetry morphology, 395-396 sex differences, 396 principle, 175 reconstruction templates, 180 regions of interest, 179-180 Computers aphasia rehabilitation artificial intelligence programming, 594-595 efficacy, 590-591 limitations in therapy, 586-590 776 Index Computers ( c o n t i n u e d ) microworld therapy, 595 modeling of aphasia, 586 patient factors, 589 properties of treatment conventional, 587-588 discrete, 587 finite, 588 isolated, 588 reading comprehension therapy, 591-592 self-help groups, 593-594 task structure drill and practice, 589 simulation, 590 stimulation, 589 tutorial, 590 verbal output therapy, 592-593 writing therapy, 592 software for assessment and rehabilitation internet resources, 618-620 listing of programs and providers, 620-640 terminology, 605 transcript analysis, s e e Child Language Data Exchange System Conceptual representations, multilinguals, 426-427 Concreteness effect aphasic patients, 239 mechanisms, 239-240 Conduction aphasia, features, 169-170 Connectionist model, s e e Neural network modeling Conversation, s e e Discourse Conversational analysis, traumatic brain injury, 490-491 Cool Spring Software, The Naming Test, 622 COPIA, 623 COPROE 623 Corpus callosum anatomy of connections, 398, 410 developmental asymmetry, 402-403 fiber types and regional differentiation, 399-400 individual variability, 400 phylogeny of asymmetry, 403-404 sex differences, 400 split-brain patient evaluation, 411-4 13 structure relationship to brain asymmetry, 401- 402 Cortex, s e e Cerebral cortex Corticosteroid therapy, Landau-Kleffner syndrome, 510 COVAT paradigm, attention testing, 276, 280 Creutzfeldt-Jakob disease (CJD) clinical characteristics and etiology, 458-459 cognitive changes, 459 speech and language changes, 459 Criterion-referenced measurement content validity, 63 content valid parallel tests, 64 degree f competence, 64 mastery, 64 representative samples, 63-64 stratification of domains, 63 Cross-Language Agrammatism Study (CLAS), 223-224 CT, s e e Computed tomography Cuban Americans, FAS Controlled Association Test performance, 74 CURE-Software, 623 CVLT, s e e California Verbal Learning Test D Darwin, Charles, contributions to neurolinguistics, 603-604 DAT, s e e Dementia of the Alzheimer type Deaf, event-related potential studies of language processing, 119-120 Deep alexia, recovery patterns, 567 Deep dysgraphia characteristics, 564-565 treatment studies, 568-569 Deep dyslexia connectionist model, 237-238, 353 features, 237 functional impairment types, 563 history of research, 14-15 phonological dyslexia comparison, 562-563, 565-566 recovery patterns, 566-567 right hemisphere disconnection syndrome, 381- 383 treatment studies, 568 Deficit space, s e e Neurolinguistic deficit space Dementia of the Alzheimer type (DAT) attention disorder, 285 auditory skills, 465 central executive role in language processing, 295-296 consistency in item performance, 244 discourse impairments, 272-273, 467-469 evolution of linguistic changes, 469-470 influence on language impairment memory problems, 471-472 visuoperceptual problems, 471 lateralization of brain function, 364 naming task performance, 466 neuropathology, 472-473 Index 777 phonological and syntactic abilities, 466 prevalence, 463-464 reading skills, 465 semantic abilities, 466-467 semantic priming effects, 245-247 specificity of linguistic changes, 470-471 speech patterns, 310 subtyping by language impairment, 472 testing of linguistic changes, 464 verbal fluency task performance, 467 writing skills, 469 Dementia, s e e s p e c i f i c d e m e n t i a s Depression effect on aphasia recovery, 539 speech patterns in patients, 309-310 Diachrony, oral versus written language, 21-23 Diagram-makers, history and validity, 43-45, 47, 58 Diaschisis, regression, 542-543 Dichotic listening task attention testing, 276-277 lateralization studies in infants, 360-362, 366 Disconnection syndrome, s e e Right hemisphere disconnection syndrome Discourse American Sign Language features, 316 impairment in right-hemisphere-damaged signers, 326 analysis in traumatic brain injury efficiency, 487 global coherence, 488-489 local coherence, 487-488 conversational discourse aspects, 265-266 definition, 265 elements, 266-267 impairments aphasia, 268-269 classification, 267-268 dementia of the Alzheimer type, 272-273, 467-469 right-hemisphere-damaged patients individual differences, 271,274 inferential deficit, 272 nonliteral language, 271 surface linguistic impairment, 270-271 narrative discourse cognitive processing, 263-265 conceptual level, 265 definition, 262 short-term memory role, 263-264 structure versus content, 263 transcript analysis, 613 Discourse Comprehension Test, features, 77 Dissociations classical dissociation, 65 double dissociation, 65-66, 69 statistical demonstration in single-case studies, 68-69 strong dissociation, 65 trend dissociation, 65 Distance effect, number comparison, 332-333 Down's syndrome (DS) language deficits comprehension, 517 delays in development and causes, 516-517 evaluation, 517 neuroanatomical features, 516 DS, s e e Down's syndrome Dual-route model, s e e Right hemisphere disconnection syndrome Dysgraphia, s e e Deep dysgraphia; Surface dysgraphia Dyslexia, s e e a l s o Attentional dyslexia; Deep dyslexia; Neglect dyslexia; Phonological dyslexia; Surface dyslexia acquired versus developmental dyslexias, 573 causal architecture, 574-575 centralist hypotheses, 580-583 cognitive modeling, 574-575 orthographic development, 583 peripheralist hypotheses auditory processes, 578-579 low-level visual processes, 576-577 phonological processes, 579-580 visual orthographic processes, 577-578 Dyslexia Screening Instrument, 623 E Echo-planar imaging (EPI), s e e Functional magnetic resonance imaging EEG, s e e Electroencephalogram Electroencephalogram (EEG), s e e a l s o Event- related potentials intracarotid sodium amytal test, 193, 196, 198 Landau-Kleffner syndrome findings, 508-509 E-mail, s e e Internet EMFs, s e e Evoked magnetic fields Emotion affect, 302 cortical-subcortical circuit, 166 expression in language, 304-305, 311 hemispheric specialization, 306-309 James-Lange theory, 303 language relationships, 301-304 778 Index Emotion ( c o n t i n u e d ) mood, 302 prosody, 305, 307-308 speech patterns in depression, 309-310 thought relationships, 303-304 EPI, s e e Echo-planar imaging Epilepsy, s e e Landau-Kleffner syndrome ERPs, s e e Event-related potentials Event-related potentials (ERPs) advantages and limitations in neurolinguistic research, 98-99 attention studies, 286 brain function localization studies, overview, 100 developmental studies in infants and children, 120-121 electrode placement, 97, 100, 108 history in language research, 95-96 Landau-Kleffner syndrome, 512-513 language processing studies, overview, 99-100 lateralization in infants, 359, 365-366 left anterior negativity effects, 119 linguistic versus cognitive phenomena, 123 MisMatch Negativity, 107 motor suppression in data acquisition, 98-99 noun/verb dissociation, 101-102, 108 origin of electroencephalogram, 96 phonological processingstudies, 106-107 Principal Components Analysis-Analysis of Variance, 99, 122-123 reading hemispheric processes in reading and dyslexia, 121-122 phonological versus semantic access, 121 second language studies, 119-120 semantic processing analysis N400 sensitivity, 112, 114, 116-117, 119 wave components, 115-116 signal averaging, 96 syntactic processing analysis P600 sensitivity, 114-116 wave components, 115-116 waveform, 96-97 word-class studies, 102-103, 105-106, 108 word concreteness studies, 102 Evoked magnetic fields (EMFs), s e e Magnetoencephalography Evoked potential, word retrieval task studies, 10 EXDEN, 624 Exler, 624 Eye tracking attention studies, 279-280 language processing information, 91 F FAS Controlled Association Test features and applications, 81 performance of Cuban Americans, 74 fESB, s e e Focal electrical stimulation Flectional, features of language, 23 Flow-chart diagrams fMRI, s e e Functional magnetic resonance imaging Focal electrical stimulation (fESB) brain surgery applications, 125 comparison with other mapping techniques, 128 history of development, 127-128 individual variation, 129 language processing components, 129-130 linguistic phenomena association, 130 psychic phenomena association, 130 techniques advantages and disadvantages, 126-127 types, 126 Fonex, 624 Foreign accent syndrome (FAS), prosody disturbances, 216 Frontal lobes attention functions, 283 history of study, 39, 41 language role, 438 word retrieval, 8-9 Frontotemporal dementia (FTD) clinical characteristics and etiology, 451 cognitive changes, 451-452 speech and language changes, 452-453 FTD, s e e Frontotemporal dementia Functional information processing brain imaging studies, 241 impairments, 240-241 implications for lexical semantics, 241-242 Functional magnetic resonance imaging (fMRI) blood-oxygenation level-dependent effect, 134 correlational approach to brain activation, 139- 140 damaged brain studies activating damaged brains, 141-142 resting state studies, 140-141 echo-planar imaging, 134-135 resolution, 134-135 sensitivity, 134 G Gall, Franz Joseph, contributions to neurolinguistics, 32-33, 38-40 GB theory, s e e Government and Binding theory Genetic potential of replacement, stroke recovery, 24 Index 779 Glossome Database, conception, 615-616 Government and Binding (GB) theory, 116-117, 250, 252 Grammar, multilinguals, 428 Group-study approach, 58-59, 61 GrundSchulSoftware Jansen, 625 GUS-Multimedia Speech System, 625-626 H Handedness effect on aphasia recovery, 538 hemispheric specialization of language, 200-201 Hartley, David, contributions to neurolinguistics, 32 HD, s e e Huntington's disease Head, Henry, contributions to neurolinguistics, 49, 51-53 Head turning, lateralization studies in infants, 359-360 Hemispheric specialization aging effects aphasia types with age, 364-365 behavioral changes, 363-364 confounding factors in study, 367-368 dementia of the Alzheimer's type, 364 differential decline in cognition, 366 physiological changes, 363 bilinguals, 202-203, 421-422 consonant-vowel-consonant identification testing, 412-413 corpus callosum anatomy of connections, 398, 410 developmental asymmetry, 402-403 fiber types and regional differentiation, 399- 400 individual variability, 400 phylogeny of asymmetry, 403-404 sex differences, 400 structure relationship to brain asymmetry, 401-402 corticolimbic evolution, 165 deaf signers, 202-203, 317-320, 323-329 emotion, 306-309 epileptics, 201 evaluation, s e e Intracarotid sodium amytal test handedness studies, 200-201,386 holistic semantic representation, 164 individual variation, 163-164 interhemispheric communication complementation of hemispheric superiority, 408-410 explicit transfer, 377-378 implicit transfer and lexical priming, 378-379 mechanisms, 410--413 language and left hemisphere domination, 164- 165, 171, 386-387, 406-407 lateralization in development auditory perception studies, 360-362, 366 childhood laterality, 361-362 confounding factors in study, 367-368 electrophysiological asymmetries, 359, 365- 366 head turning and postural asymmetry in infants, 359-360 hemispherectomy studies in children, 362 maturational gradients, 358-359 morphological asymmetry in immature brain, 358 motor activities in infancy, 360 overview, 357-358 memory systems, 171 motivational basis, 163, 172 neuromodulation, 164, 171 number processing, 340-341 perisylvian regions, anatomical asymmetry imaging and functional laterality correlation, 395-396 individual variability, 396-398 planum temporale morphology, 397-398 sex differences, 396 Sylvian fissure morphology, 393-394, 396- 398 prosody, 213-216, 307-308 reading comprehension in dyslexia, 121-122 recovery of language and right hemisphere role, 385-392 sign language studies, 202-203 speech perception, 217-218 Herpes encephalitis, category retrieval deficits in patients, 16 Hippocampus, role in memory, 167 Hood, Alexander, contributions to neurolinguistics, 34-38, 43 Huntington's disease (HD) clinical characteristics and etiology, 453 cognitive changes, 453 confrontation naming and repitition, 455 gaps in literature studies, 456 reading and writing performance, 455-456 speech comprehension, 455 verbal communication, 454-455 I Inferior thalamic peduncle (ITP), language role, 438-439 780 Index Information-processing approach overview, 59-60 tests, 76 INTACT, 626 Interaction activation model, s e e Neural network modeling Interference, mapping of neurolinguistic deficit space, 90 Internet introduction, 655-656 libraries and bookstores, 656-658 Listserv listing of neurolinguistics resources, 662-664 overview, 660-661 posting, 661 searching for mailing addresses, 661 subscribing, 661 unsubscribing, 661 newsgroups, 660 publishers and journals, 658-660 search engines, 656 software resources, 618-620 Uniform Resource Locators for neurolinguistics, 655, 664-667 World Wide Web, 655 Intracarotid sodium amytal test (ISA) anesthesia adequacy, determination, 196 development, 189-190 drug administration, 195-199 electroencephalography, 193, 196, 198 epileptics, 201 hemispheric language dominance bilinguals, 202-203 criteria for establishment, 197 handedness studies, 200-201 sign language studies, 202-203 imaging, 191, 193, 198 memory and language tasks, 193-194 patient selection, 195 principle, 191-192 protocols, 192-193, 203 timing of stimulus presentation, 196-197 ISA, s e e Intracarotid sodium amytal test Isolated tongues, features of language, 22-23 Item difficulty, 66 ITE s e e Inferior thalamic peduncle ITS-Integriertes Therapie System, 626-627 J Jackson, John Hughlings, contributions to neurolinguistics, 49-50 Journals, neurolinguistics internet resources, 658-660 listing, 642-644 L Lallemand, Claude-Francois, contributions to neurolinguistics, 40-41 LAN, s e e Left anterior negativity Landau-Kleffner syndrome (LKS) clinical features, 508-510 corticosteroid therapy, 510 discovery, 507-508 electroencephalography, 508-509 linguistic impairment behavioral data, 513-514 event-related potentials in analysis, 512-513 testing, 511-512 prognosis, 510-511, 514 Language, hierarchical definition, 84-86 Lateralization, s e e Hemispheric specialization Laureate Learning Systems, 627 Left anterior negativity (LAN), processing of fillers in working memory, 119 Left hemisphere dominance, s e e Hemispheric specialization Left-to-right transfer hypothesis clinical implications, 391-392 evidence, 387 language compensation degree, 390 mechanism of transfer, 390-391 LeMo, 627 LernReha Programme, 629 Lernsoftware, 629 Lesion analysis anomia, 132 aphasia, 131-132, 169-170, 182-183 history, 173 imaging computed tomography versus magnetic resonance imaging,174 reconstruction templates, 180 regions of interest, 179-180 time post-onset to scan, 178 noun naming deficit, 3-4, 8-10 recovery, 185-187 review articles, 181-182 semantic deficits, 183-184 size versus site in recovery, 186 speech production, 185 syntactic processing deficits, 184 time post-onset to language testing, 178-179 treatment response evaluation, 186 verb naming deficit, 3-4, 8-10 LETRAS, 623 Lexical access agrammatism, 228, 230, 233-234 impairment, distinguishing from loss of semantic knowledge Index 7 81 consistency in performance, 244, 247 semantic priming, 244-247 phonology role, 217 Lexical Access Model, 630-631 Lexical cohesion, deficits in psychosis, 500-501 Lexical defect hypothesis, 6-8 Lexical meaning nondecompositional model, 244-245 perceptual versus functional information processing, 241-242 three-dimensional model, 242, 238 Lexical priming, s e e Priming Lexical representations, multilinguals, 426-427 Lexical semantics definition, 101 event-related potential studies, 101-103, 105- 109 noun/verb dissociation, 101-102 LE 630 LFPREE 630 LFPRON, 630 Lies mit, 631 Limbic brain circuits, 166 corticolimbic evolution and asymmetry, 165 functions and ontogenesis, 18-19 vertical organization of brain, 161-162 Lingraphica System, 631-632 LingWare Therapiesysteme, 632 Listserv, s e e Internet LKS, s e e Landau-Kleffner syndrome Lt~becker Lernprogramme, 632 M Magnetic resonance imaging (MRI), s e e a l s o Functional magnetic resonance imaging corpus callosum asymmetry, 401 lesion analysis, 175-178 perisylvian regions, anatomical asymmetry morphology, 395-396 sex differences, 396 principle, 175-176 reconstruction templates, 180 regions of interest, 179-180 Magnetoencephalography (MEG) comparison to other imaging techniques, 148, 156 evoked magnetic fields correlation with event-related potentials, 147- 148 N400m localization, 151-152 picture-naming tasks, 154, 156 semantic categorization tasks, 154, 156 sound discrimination studies, 149-151, 156 instrumentation, 145-147 inverse problem solution, 147, 149, 152 origin of signal, 144-145 resolution and sensitivity, 148, 157 signal averaging, 145-146 source localization, 147-148 Mania cognitive explainations of communication abnormalities, 501-503 cognitive/neurolinguistics approach for communication abnormalities, 503-504 speech comparison to aphasia, 498 complexity-related deficits, 499-500 lexical cohesion deficits, 500-501 unclear reference, 500-501 thought disorder, Bleularian view, 496-497 Mapping, s e e Focal electrical stimulation; Functional magnetic resonance imaging; Lesion analysis; Magnetoencephalography; Neurolinguistic deficit space; Positron emission tomography Marie, Pierre, contributions to neurolinguistics, 44 Markedness theory, 209 Matery testing, s e e Criterion-referenced measurement McCloskey's model, s e e Number processing Medieval Cell Doctrine, 28 MEG, s e e Magnetoencephalography Memory, s e e a l s o Working memory hemispheric specialization of memory systems, 171 hippocampal memory system, 167 organization of verbal information in Parkinson's disease, 478-479 senescence, memory types affected, 22 ventrolateral circuit, 167 Mental lexicon, definition, 235-236 Meynert, Theodor, contributions to neurolinguistics, 45-47 MicroCog, 632 Microworlds, computer therapy in aphasia, 595 Minnesota Test for Differential Diagnosis of Aphasia (MTDDA), features and applications, 79-80 MisMatch Negativity (MMN), definition, 107 MMN, s e e MisMatch Negativity Model-building, neurolinguistics, 92-93 Morphology aphasia, 221-222 sentence processing, 222-228 single-word processing, 229-233 transcript analysis, 612-613 782 Index Motility, role in brain evolution, 160-161, 168- 169 MRI, s e e Magnetic resonance imaging MTDDA, s e e Minnesota Test for Differential Diagnosis of Aphasia Multilingual Aphasia Examination, features and applications, 80 Multilingualism aphasia recovery patterns, 417-420 distinctions to be made in studies grammar and pragmatics, 428 lexical and conceptual representations, 426- 427 linguistic and neurolinguistic levels of description, 425-426 linguistic competence and metalinguistic knowledge, 428-429 hemisphere dominance of language, 202-203, 421-422 language processing and representation compared to unilinguals, 422-424 Myelinogenetic fields of Flechsig, maturation, 19 N N400, s e e Event-related potentials N400m, s e e Magnetoencephalography Naming task, s e e a l s o Noun naming deficits; Picture-naming; Verb naming deficits agrammatism, verb naming deficits, 5 anomia, noun naming deficits, 5 dementia of the Alzheimer type, 466 lesion analysis of deficits, 3-4, 8-10, 440-441 Parkinson's disease, 477-478 Narrative discourse, s e e Discourse Natural errors, language processing information, 91 NCCEA, s e e Neurosensory Center Comprehensive Examination for Aphasia Neglect dyslexia features, 283-284 thalamic lesion association, 441-442 Neural network modeling attention, 277 backprop algorithm, 351 Boltzmann Machine algorithm, 351 components of system, 345 computing elements, 345-346 deep dyslexia, 353 deficiencies of connectionist models, 355 feedforward architecture, 347, 351-352 hard-wired networks deep dysphasia, 350-351 interaction activation model, 349 structured connectionist model, 349-350 language therapy, planning and evaluation, 70 overview, 343-344 recurrent architecture, 347, 352-353 simple recurrent network, 353 supervised learning networks, 347, 351-353 unsupervised learning networks, 347, 354 Neurochemistry, cognitive processing limitations, 552-553 Neuroimaging, s e e Computed tomography; Functional magnetic resonance imaging; Magnetic resonance imaging; Magnetoencephalography; Positron emission tomography Neurolinguistic deficit space direct measures in mapping, 87-88 discrimination measures, 89-90 interference in mapping, 90 priming in mapping, 90 reaction time measures, 88-89 Neuroplasticity aphasia recovery limitations in recovery, 551 role, 550 learning role, 550-551 Neurop-Neuropsychologische Batterie, 632 Neurosensory Center Comprehensive Examination for Aphasia (NCCEA), features and applications, 81 Newsgroups, neurolinguistics, 660 Nonsemantic reading, characteristics, 563 Noun naming deficits anomic patients, 5 brain lesions, 3-4, 8-10 history of research, 4-6 lexical defect hypothesis, 6-8 noun/verb dissociation, event-related potential studies, 101-102, 108 semantic defect hypothesis, 6-8 NR, s e e Nucleus reticularis Nucleus reticularis (NR), language role, 438-439 Number processing algebraic knowledge, 341 hemispheric specialization, 340-341 McCloskey's model features, 333-335 problematic cases, 335-337 notation of numbers, 331-332 quantity representation and distance effect in number comparison, 332-333 triple-code model, 337-340 Index 783 O Open-class words, s e e Word-class Optic aphasia, right hemisphere disconnection syndrome, 380-381 Orthographic development, dyslexia, 583 P P600, s e e Event-related potentials Paced Auditory Serial Attention Test, 633 PAL, s e e Psycholinguistic Assessment of Language Parallel distributed processing, 438 Parkinson's disease (PD) clinical features, 475-476 cognitive deficits, 476, 482 memory, organization of verbal information, 478-479 syntax comprehension deficits, 435-436, 480- 482 treatment side effects and linguistic function, 482-483 verbal fluency and naming deficits, 477-478 Parrot Software, communication disorders, 633 PCA-ANOVA, s e e Principal Components Analysis-Analysis of Variance PD, s e e Parkinson's disease Perceptual information processing brain imaging studies, 241 impairments, 240-241 implications for lexical semantics, 241-242 Perisylvianregions, anatomical asymmetry imaging and functional laterality correlation, 395-396 individual variability, 396-398 planum temporale morphology, 397-398 sex differences, 396 Sylvian fissure morphology, 393-394, 396-398 Persistent Hyperinsulineric Hypoglycemia of Infancy (PHHI) clinical features, 521 language features, 521-522 PET, s e e Positron emission tomography PH, s e e Psychological hypotheses PHHI, s e e Persistent Hyperinsulineric Hypoglycemia of Infancy Phonetic deficit segmental coarticulation, 211-212 speaking rate performance in aphasia, 212 subtle phonetic deficit in posterior aphasics, 212-213 types in aphasia, 210-211 PHONO, 637 Phonological agraphia, characteristics, 564 Phonological deficit markedness theory, 209 sonority sequencing principles, 210 syllable structure, 209-210 types in aphasia, 208-209 underspecification theory, 209 Phonological dyslexia centralist hypotheses, 581-582 characteristics, 562 phonological processes, 579-580 recovery patterns, 566-567 treatment studies, 568 Phonological loop, s e e Working memory Phonological store, s e e Working memory Phonology, transcript analysis, 613-615 Phrenology, contributions to neurolinguistics, 34-38 PICA, s e e Porch Index of Communicative Ability Pick, Arnold, contributions to neurolinguistics, 49-51 Pick's disease, s e e Frontotemporal dementia Picture-naming, magnetoencephalography studies, 154, 156 Pitres, contributions to neurolinguistics, 4-5, 8 Place of articulation (POA), brain localization of discriminations, 107 Planum temporale, morphology, 397-398 POA, s e e Place of articulation Porch Index of Communicative Ability (PICA), features and applications, 77-78 Porencephaly clinical features, 523 language features, 523 Positron emission tomography (PET) aphasia recovery studies, 542-545 regional cerebral blood flow studies, s e e Regional cerebral blood flow resolution, 133 sensitivity, 133 tracer isotopes, 132 PPA, s e e Primary progressive aphasia Pragmatics analysis in traumatic brain injury comprehension, 490 overview, 489-490 production, 490 hemispheric specialization, 309 multilinguals, 428 Primary progressive aphasia (PPA) clinical characteristics and etiology, 238, 459- 460 speech and language changes, 460 784 Index Priming implicit hemispheric transfer and lexical priming, 378-379 mapping of neurolinguistic deficit space, 90 phonological priming and event-related potentials, 106-107 semantic priming in distinguishing impairment from loss of semantic knowledge, 244-247 Principal Components Analysis-Analysis of Variance (PCA-ANOVA), event-related potential analysis, 99, 122-123 Progressive supranuclear palsy (PSP) clinical characteristics and etiology, 456-457 cognitive changes, 457 confrontation naming and repitition, 458 gaps in literature studies, 458 reading and writing performance, 458 speech comprehension, 458 verbal communication, 457 Prosody basal ganglia role, 308 deficits in aphasia, 213 disturbance in foreign accent syndrome, 216 emotional expression by language, 305, 307 hemispheric specialization, 213-216, 307- 308 intonation in aphasic patients, 215-216 perception, s e e Speech perception right hemisphere role, 407 stress deficit studies, 213-214 tonal coarticulation, 215 tonal paraphasias, 214-215 PSR s e e Progressive supranuclear palsy PsychLab, 637-638 Psycholinguistic Assessment of Language (PAL), information-processing approach, 76 Psychological hypotheses (PH), development, 61-62 Psychosis, see a l s o Mania; Schizophrenia cognitive explainations of communication abnormalities, 501-503 cognitive/neurolinguistics approach for communication abnormalities, 503-504 neuropathology of linguistic deficits, 505-506 speech comparison to aphasia, 498 complexity-related deficits, 499-500 lexical cohesion deficits, 500-501 unclear reference, 500-501 thought disorder, Bleularian view, 496-497 Pure alexia features, 560-561 right hemisphere disconnection syndrome, 379- 380 treatment studies, 569 Q Quantity representation, distance effect in number comparison, 332-333 R Random assignment, 66-67 Randomization tests single-subject studies, 67-68 software, 68 Random sampling, 66-67 rCBE see Regional cerebral blood flow Reaction time measures, mapping of neurolinguistic deficit space, 88-89 Reading comprehension computer therapy in aphasia, 591-592 dementia of the Alzheimer type, 465 disorders, see spec i f i c d i s o r d e r s event-related potential studies, 122 hemispheric processes in reading and dyslexia, 121-122 pathways to reading, 560 phonological versus semantic access, 121 Recovery, aphasia beneficial versus detrimental changes in brain, 554-555 bilateral lesion effects, 387-389 cognitive neuropsychological approach to rehabilitation, 548-549 computers in aphasia rehabilitation artificial intelligence programming, 594-595 efficacy, 590-591 limitations in therapy, 586-590 microworld therapy, 595 modeling of aphasia, 586 patient factors, 589 properties of treatment conventional, 587-588 discrete, 587 finite, 588 isolated, 588 reading comprehension therapy, 591-592 self-help groups, 593-594 task structure drill and practice, 589 simulation, 590 stimulation, 589 tutorial, 590 verbal output therapy, 592-593 writing therapy, 592 Index 785 epidemiological approaches in study, 536 genetic potential of replacement, 24 language lateralization, 386-387, 389-390 left-to-right transfer hypothesis clinical implications, 391-392 evidence, 387 language compensation degree, 390 mechanism of transfer, 390-391 lesion analysis, 185-187 mechanisms of recovery functional takeover, 542-544 overview, 541 regression of diaschisis, 542-543 multilinguals, patterns of recovery, 417-420 neurochemical thresholds and cognitive processing limitations, 552-553 neuroplasticity learning role, 550-551 limitations in recovery, 551 recovery role, 550 positron emission tomography studies, 542- 545 prognostic factors in spontaneous recovery age, 537 aphasia severity, 540-541 depression, 539 education, 538 gender, 537 handedness, 538 hemispheric asymmetries, 538-539 lesion factors etiology, 539 site, 539-540 size, 539 linguistic background, 538 time post-onset, 541 restoration and substitution of function, 549- 550 spontaneous recovery versus rehabilitation, 553 syntax relearning, 555-556 time course, 554 Regional cerebral blood flow (rCBF) activation tasks, 133-136 damaged brain studies activating damaged brains, 141-142 resting state studies, 140-141 data acquisition, s e e Positron emission tomography principle of neural activity quantification, 132- 133 subtraction method limitations, 136, 138 word retrieval task studies, 10 RehaCom, 638 Resources, neurolinguistics book listing, 644-652 history of nerolinguistics, 53-54 internet, s e e Internet journal internet resources, 658-660 listing, 642-644 software internet resources, 618-620 listing, 620-640 sourcebooks, 652-653 Revised Token Test (RTT), features and applications, 81 RHD, s e e Right-hemisphere-damaged Rhinic brain, functions and ontogenesis, 18-19 Right-hemisphere-damaged (RHD) attention deficits, 286-287 discourse impairments individual differences, 271,274 inferential deficit, 272 nonliteral language, 271 surface linguistic impairment, 270-271 prosody role, 407 Right hemisphere disconnection syndrome case studies of speech, 374-376, 383 deep dyslexia, 381-383 dynamic language competence in partial disconnection, 376 features of commissurotomy patients, 370-371 interhemispheric relations explicit transfer, 377-378 implicit transfer and lexicality priming, 378- 379 optic aphasia, 380-381 pure alexia, 379-380 word recognition and dual-route analysis, 371- 372, 374 Rommel, Peter, contributionsto neurolinguistics, 31 RTT, s e e Revised Token Test S Schenck, Johannes, contributions to neurolinguistics, 29 Schizophrenia attention movement without eye movement, 280-281 cognitive explainations of communication abnormalities, 501-503 cognitive/neurolinguistics approach for communication abnormalities, 503-504 neuropathology of linguistic deficits, 505-506 786 Index Schizophrenia ( c o n t i n u e d ) speech compaCson to aphasia, 498 complexity-related deficits, 499-500 lexical cohesion deficits, 500-501 unclear reference, 500-501 thought disorder, Bleularian view, 496-497 Schmidt, Johann, contributions to neurolinguistics, 31 Search engine, s e e Internet Second language, event-related potential studies, 119-120 Selective attention, s e e Attention Semantic defect hypothesis, 6-8 Semantic dementia, features, 238-239 Semantic paraphasia, features, 236-237 Semantic priming, s e e Priming Semantic processing dementia of the Alzheimer type, 466 event-related potential studies, 112, 114-117, 119-120 lesion analysis of deficits, 183-184 magnetoencephalography studies, 154, 156 multiple modality-specific systems, 242-243 Senescence central executive role in language processing, 297 effects on brain lateralization aphasia types with age, 364-365 behavioral changes, 363-364 confounding factors in study, 367-368 dementia of the Alzheimer's type, 364 differential decline in cognition, 366 physiological changes, 363 memory types affected, 22 Sentence comprehension linguistic-descriptive approach case-deficit hypothesis, 252 trace-deletion hypothesis, 250-252 processing approach capacity limitation, general versus specific, 254-255 mapping deficit versus limited capacity, 252- 254 working memory role phonological short-term memory in first-pass language processing, 291-292 phonological short-term memory in second- pass language processing, 292-293 semantic short-term memory, 293-295 syntactic short-term memory, 293-295 Sentence processing agrammatism, 222-223, 230-231,250-260 Cross-Language Agrammatism Study, 223-224 lexical representation and access, 228 parametric variation of languages, 224-228 Sentence production, s e e Agrammatism Short-term memory (STM), s e e Working memory Sign language, s e e American Sign Language Simple recurrent network, s e e Neural network modeling Single-case-only approach, 60 Single-case studies overview, 60 randomization tests, 67-68 random sampling versus random assignment, 66-67 statistical demonstration of dissociations, 68-69 Single-word processing, aphasia comprehension of speech, 229-230 limited processing resources, 232 production of speech, 229-231 writing, 232 SMA, s e e Supplementary motor area Sodium amytal test, s e e Intracarotid sodium amytal test Software, s e e Computers; s p e c i f i c p r o g r a m s Sonority, sequencing principles, 210 Sourcebook listing, neurolinguistics, 652-653 Speaking rate, performance in aphasia, 212 Speech perception deficits in aphasia, 216-217 hemispheric specialization, 217-218 intonation, 217 phonology role in lexical access, 217 stress studies, 217 tone, 218 Speech production computer therapy in aphasia, 592-593 working memory role, 298 Spelling disorders, 564-565 fingerspelling in sign language, 316-317 pathways, 563-564 Split-brain, s e e Corpus callosum SprechSpiegel, 626 Steno, Nicolaus, contributions to neurolinguistics, 31-32 STM, s e e Short-term memory Stress, prosody deficit studies perception of speech, 217 production of speech, 213-214 Stroop task, attention testing, 276 Sturge-Weber syndrome clinical features, 522 language features, 522 Index 787 Supervised learning networks, s e e Neural network modeling Supplementary motor area (SMA) control, 168 speech function, 170 Supralimbic brain, functions and ontogenesis, 18- 19 Surface dysgraphia characteristics, 564 treatment studies, 569-571 Surface dyslexia centralist hypotheses, 581-582 characteristics, 561-562 history of research, 14 treatment studies, 569-571 Suvalino, 638 Sylvian fissure, morphology and variability, 393- 394, 396-398 Syntactic processing dementia of the Alzheimer type, 466 disorders in aphasia agrammaqtic production, 256-260 sentence comprehension, 250-255 sentence production, 255-256 event-related potential studies, 112, 114-117, 119-120 Government and Binding theory, 116-117 lesion analysis of deficits, 184 Parkinson's disease, comprehension deficits, 435-436 relearning in aphasia recovery, 555-556 Syntax, transcript analysis, 612-613 T TBI, s e e Traumatic brain injury TDH, s e e Trace-deletion hypothesis Temporal lobe role in aphasia recovery, 185-186 word retrieval, 8-9 Temporal planum, ontogenesis, 18 Testing, language comprehension and production, s e e a l s o s p e c i f i c t e s t s comprehensive tests, 77-80 - rationales academic-experimental rationale, 72-73 aphasia severity, 75-76 type determination, 75 communication ability of patients, 77 differential diagnosis, 74-75 information-processing approach, 76 normalcy determination, 73-74 specific tests, 80-81 standardization difficulties, 71-72 types of tests, 77, 82 word-fluency tests, 81 Text & Co., 638-639 Thalamus, language role category-specific naming deficits after lesion, 440-441 functional neuroimaging, 444 historical perspective, 436-437 neglect dyslexia after lesion, 441-442 selective engagement of cortical mechanisms, 437-440, 443 Theory of mind hypothesis, s e e Autism Tone, s e e Prosody Trace-deletion hypothesis (TDH), 250-252 Transcript analysis, s e e Child Language Data Exchange System Traumatic brain injury (TBI) aphasic disturbances, overview, 485-486 conversational analysis, 490-491 discourse analysis efficiency, 487 global coherence, 488-489 local coherence, 487-488 executive function impairment in communication disturbances, 491-494 pragmatic analysis comprehension, 490 overview, 489-490 production, 490 Triple-code model, s e e Number processing TS, s e e Turner syndrome Turner syndrome (TS) anatomical features, 520 cognitive impairments, 520 incidence, 520 language features, 521 U Underspecification theory, 209 Uniform Resource Locator (URL), s e e Internet Unsupervised learning networks, s e e Neural network modeling URL, s e e Uniform Resource Locator V VaD, s e e Vascular dementia Vascular dementia (VaD) clinical characteristics and etiology, 448 cognitive changes, 448-449 confrontation naming and repitition, 450 gaps in literature studies, 450-451 reading and writing performance, 450 788 Index Vascular dementia (VaD) ( c o n t i n u e d ) speech comprehension, 449-450 verbal communication, 449 Verbal fluency, s e e Word-fluency testing Verb naming deficits agrammatic patients, 5 brain lesions, 3-4, 8-10 category-specific impairments, 10-11 history of research, 4-6 lexical defect hypothesis, 6-8 noun/verb dissociation,.event-related potential studies, 101-102, 108 semantic defect hypothesis, 6-8 Vico, Giovanni Battista, contributions to neurolinguistics, 4-5 Vigil Continuous Performance Test, 639-640 Visual processes, dyslexia, 576-578 Visuospatial sketchpad, s e e Working memory Vocabulary acquisition, working memory role, 298-299 Voice onset time (VOT) brain localization of discriminations, 107 phonetic deficit in aphasia, 211 VOT, s e e Voice onset time W WAB, s e e Western Aphasia Battery Wada test, s e e Intracarotid sodium amytal test Wepfer, Johannes Jakob, contributions to neurolinguistics, 29-31 Wernicke, Carl, contributions to neurolinguistics, 45-46, 58 Wernicke's aphasia age of onset, 23 jargonophasia, 23-24 recovery, 185 Western Aphasia Battery (WAB) aphasia severity assessment, 75 aphasia type classification, 75 features and applications, 79,81 scoring software, 640 Wiener Test System, 640 Williams syndrome clinical features, 518 language features, 518-520 neuroanatomical features, 518 WinWege 1996, 640 Word-class anterior-posterior distinction, 105-106 event-related potential studies, 103, 105-106, 108, 119-120 opened versus closed-class words, 102-103 Word-fluency testing, 74, 81 dementia of the Alzheimer type, 467 Parkinson's disease, 477-478 Word-frequency, effects on event-related potentials, 106 Working memory central executive role in language processing Alzheimer's disease, 295-296 aphasia, 296-297 senescence, 297 central executive, 290 definition and modeling, 289-290, 300 narrative discourse, short-term memory role, 263-264 phonological loop articulatory rehearsal process, 289 phonological store, 289-290 sentence comprehension roles phonological short-term memory in first-pass language processing, 291-292 phonological short-term memory in second- pass language processing, 292-293 semantic short-term memory, 293-295 syntactic short-term memory, 293-295 speech production role, 298 visuospatial sketchpad, 289-290 vocabulary acquisition role, 298-299 World Wide Web (WWW), s e e Internet Written language computer therapy in aphasia, 592 emotional expression, 305 invention of humankind in brain function, 19- 21 single-word processing deficits in aphasia, 232 skills in dementia of the Alzheimer type, 469 writing systems, 23 WWW, s e e World Wide Web